Nikon - TIU / TIS Inverted Microscope
TIU / TIS Inverted Microscope

Scientists have overcome many live cell imaging challenges using advanced techniques such as TIRF, confocal, FRET, photoactivation and microinjection. At the center of it all is the Eclipse Ti, a powerful inverted microscope system that provides instant access to all of these techniques plus revolutionary Nikon CFI60 optics. Available in three models, the Eclipse microscope Ti series offers improved system speed, increased flexibility and efficient multi-mode microscopy as part of a fully-integrated microscope system that is ideal for high-end research and live cell imaging.

TIU / TIS Inverted Microscope

Enhanced Operability

All buttons and control switches for motorized operation are designed considering ease of operation, visibility and understandability. Users can concentrate on their research without being hindered by microscope operations.

Operation Buttons on Both Sides and Front of the Microscope Body

Fluorescence filter changeover, objective changeover, objective retraction, Z-axis coarse/fine changeover, PFS on/off control and offset storage, diascopic illumination on/off control can be operated quickly with easy-to identify buttons on the microscope body.

Newly Developed Joystick and Ergonomic Controllers

High-speed motorized XY stage and Z-axis can be controlled using the joystick or ergo controller units. The joystick also allows a custom programmed speed adjustment with precise and natural operational feel.

VFD Screen and Operation Buttons on the Front of the Microscope Body

Microscope status including attached objective information and on/off condition of the PFS can be confirmed on the display at a glance.

PFS Offset Dial

The PFS offset is within easy reach to facilitate control. Coarse/fine switching is possible with simple button operation.

Remote Controller Touch Panel and Preset Buttons

The microscope can be operated and microscope status is confirmed with icons. Also, observation conditions can be memorized with preset buttons. This enables switching observations from phase contrast to fluorescence with a single touch of a button, allowing the user to concentrate on observation without stress or averting attention from the task.

Sophisticated Original Slant Design

By inclining the front part of the microscope’s body slightly backward the distance between the operator’s eyepoint and the specimen has been reduced by about 40mm, improving visibility and ergonomic design.

Observation Methods

Nikon’s uncompromising optical technologies provide diverse multi-modal visual information of a specimen using any observation method, delivering the full range of cellular details to researchers.

Nomarski DIC

The perfect balance of high contrast and high resolution is imperative for the observation of smaller structures. Nikon’s unique DIC system is designed to achieve uniform high-resolution images even at low magnifications. The new DIC sliders (dry types) include high-resolution and high-contrast choices.

A filter cube style DIC analyzer can be mounted on the motorized filter turret to minimize switching time between DIC observation and fluorescence observation.

Phase Contrast

For critical phase contrast observation, the CFI Plan Fluor ADH 100x (Oil) objective is available. This objective reduces halos and doubles the contrast of minute cell detail compared to conventional phase contrast objectives. It enables phase contrast observation of specimens with low-contrast minute structures within the cell.


Use of high NA condenser allows darkfield observation. Long-term observation of nanoparticles without photobleaching is possible.

Hoffman Modulation Contrast®

The combination of dedicated HMC objectives and HMC condenser components creates high contrast 3D-like images without halos, of living transparent specimens grown in plastic dishes.

New Objectives

CFI S Plan Fluor ELWD/ELWD Phase Contrast Objectives

Plan Apochromat Objective 20x

High-speed Motorized Control and Acquisition

Enhanced Speed of Individual Motorized Components

Digital Controller Hub Significantly Increases Motorized Accessory Speed

Remarkably Fast Image Acquisition


Dust Cover

Power code


Allen Keys